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  TILMICOSIN BASE

Chemical Formula: C46H80N2O13
Molecular Weight: 869.15

Structural Formula : C46H80N2O13
Description:  white or off-white crystalline powder
Purity: ¨R 85%(dry weight basis)
Standard: USP 26
CAS NO.:108050-54-0

Analysis ltem

Specification
Analysis result

Assay %

85min

90.2

Moisture %

5.0max

4.6

Heavy metal ppm

20max

Qualified

Residue on ignition %

2.5 max

1.3

Cis-isomer: %

82.0-88.0

Qualified

Trans-isomer: %

12.0-18.0

Qualified

Transparency

Qualified

Qualified

Efficacy:
Tilmicosin is a macrolide antibiotic developed for veterinary use. It is recommended for treatment and prevention of pneumonia in cattle, sheep and pigs, associated with Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. It is an antibiotic medicine with great antibiotic effect and broad antibiotic spectrum . Not show resistance and cross-resistance with other antibiotic often used in clinic. Mainly used in the Pleuropneumonia and the infection caused by Pasteurellaceae , Pasteurella and mycoplasma.

Dosage & Administration:
Formulations of tilmicosin include an injectable for use in cattle and sheep (30% Injection) and premix formulations for swine (4%, 10% & 20% Premix). The recommended dose of the injectable formulation in both cattle and sheep is a single subcutaneous injection of 10 mg/kg BW. Recommended dose for swine in feed is 200-400 mg/kg of feed for 10 to 21 days, equivalent to 8-20 mg/kg BW per day.

Packing: 25kg per fiber drum
Storage : Protected from light , stored hermetically and in a dry place
Shelf Life: 2 years.s


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