Intermediates 12-Bromo-1-dodecanol for critical molecular building block

Product Overview

12-Bromo-1-dodecanol is a high-value, linear organic compound serving as a critical molecular building block in pharmaceutical R&D and advanced material synthesis. Its unique structure, comprising a long alkyl chain (C12) terminated with a bromine atom and a primary hydroxyl group, provides two distinct reactive sites for sequential and diverse chemical modifications. This bifunctionality is key for constructing complex target molecules with precision.

Key Applications & Uses

Medicinal Chemistry: Excellently suited for creating macrocyclic libraries and as a spacer arm in PROTACs (Proteolysis Targeting Chimeras) linker synthesis. Its length is optimal for facilitating critical interactions in drug-target complexes.

Material Science: A fundamental monomer for producing specialized polymers, including polyethers and polyesters, and for synthesizing sophisticated surfactants and lipid nanoparticles (LNPs) for drug delivery systems.

Chemical Synthesis: The bromine atom acts as an excellent leaving group for Williamson ether synthesis or nucleophilic substitution with amines and thiols. The hydroxyl group can be independently oxidized, esterified, or used in coupling reactions.

Quality & Supply Assurance

Our 12-Bromo-1-dodecanol is manufactured under strict quality control protocols. We provide comprehensive analytical data, including NMR and HPLC purity reports, with every batch to guarantee reliability and reproducibility in your experiments. As your strategic partner in chemical innovation, we offer scalable quantities from lab to pilot scale, backed by expert technical support.

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