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Intermediates 2,4,5-Tribromo-1-methyl-1H-imidazole for critical molecular building block
Imidazole derivative intermediates
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Intermediates 2,4,5-Tribromo-1-methyl-1H-imidazole for critical molecular building block

CAS:1003-91-4 

Product purity:98% Appearance:White to light yellow solid

Product Name: 2,4,5-Tribromo-1-methyl-1H-imidazole

2,4,5-Tribromo-1-methyl-1H-imidazole is a high-purity, versatile brominated imidazole derivative extensively used as a critical molecular building block in pharmaceutical discovery and development. Its unique tribromo-substituted structure on the imidazole ring, protected by an N-methyl group, makes it an exceptionally valuable intermediate for introducing steric hindrance and electronic influence into target molecules.

This compound is primarily employed in metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations, to construct complex heterocyclic systems. It serves as a key precursor in synthesizing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. We guarantee superior batch-to-batch consistency, >98% purity (by HPLC), and reliable global supply to accelerate your R&D pipeline.

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    2,4,5-Tribromo-1-methyl-1H-imidazole: A Premium Building Block for Advanced Chemical Synthesis

    Product Overview

    2,4,5-Tribromo-1-methyl-1H-imidazole (CAS: 1003-91-4 ) is a highly functionalized, multi-halogenated imidazole scaffold designed for sophisticated chemical synthesis. As a leading global supplier, we provide this essential compound to empower innovation in medicinal chemistry and material science. Its strategic bromination pattern and N-methyl protection offer unparalleled reactivity and selectivity, making it an indispensable tool for constructing complex molecular architectures.

    Key Applications & Uses

    Pharmaceutical Intermediates: A pivotal precursor in the synthesis of potential drug candidates, especially for creating kinase inhibitors, antiviral agents, and other bioactive heterocycles.

    Cross-Coupling Reactions: Excellently suited for selective, step-wise functionalization via palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira). The bromine at the 2-position is typically the most reactive, allowing for sequential derivatization.

    Agrochemicals and Materials Science: Used in developing novel compounds for crop protection and functional materials where the imidazole core imparts specific electronic or steric properties.

    Our Quality Promise

    We understand that precision and purity are non-negotiable in R&D. Our 2,4,5-Tribromo-1-methyl-1H-imidazole is manufactured under strict quality control, delivering:

    High Purity: Consistently ≥98% purity (verified by HPLC/NMR).

    Stability: Supplied as a stable, crystalline solid with secure packaging.

    Global Logistics: Reliable and fast international shipping to ensure your research proceeds without delay.

    Contact our technical sales team today for detailed specifications, bulk quotes, and custom synthesis inquiries.

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