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Intermediates 5-Bromo-6-azauracil for critical molecular building block
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Intermediates 5-Bromo-6-azauracil for critical molecular building block

CAS:4956-05-2 

Product purity:98% Appearance: White solid

Title: 5-Bromo-6-azauracil | High-Purity Brominated Nucleobase Analog

5-Bromo-6-azauracil is a strategically brominated derivative of 6-azauracil, serving as a versatile molecular building block for pharmaceutical and agrochemical research. This high-purity compound is engineered to act as a key synthetic intermediate, particularly in nucleoside and nucleic acid chemistry. Its structure, featuring a bromine atom on the uracil scaffold, allows for efficient further functionalization via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig animations. Researchers leverage 5-Bromo-6-azauracil to develop novel thymidine mimics, enzyme inhibitors, and other bioactive molecules targeting various disease pathways. As a trusted partner in the chemical supply chain, we guarantee stringent QC, batch-to-batch consistency, and reliable global delivery to accelerate your discovery pipeline.

    5-Bromo-6-azauracil - Detailed Product Information for R&D

    Product Overview

    5-Bromo-6-azauracil is a premium-grade, bromo-functionalized nucleobase analog essential for advanced medicinal chemistry and drug discovery. This compound is specifically designed as a critical molecular building block  for constructing complex target molecules. Its core structure integrates the bioisosteric properties of aza-uracil with the synthetic versatility of a bromine atom, making it an indispensable tool for researchers developing next-generation therapeutics.

    Key Applications & Uses

    Nucleoside/Nucleotide Chemistry: A fundamental precursor for synthesizing modified nucleosides, acting as a thymine or uracil analog to probe nucleic acid interactions or develop antiviral/anticancer agents.

    Pharmaceutical Intermediates: Serves as a pivotal intermediate in creating small molecule libraries. The bromine atom is an ideal handle for palladium-catalyzed cross-coupling reactions, enabling the rapid introduction of diverse aryl, heteroaryl, and amine functionalities.

    Enzyme Inhibition: Its structure mimics natural pyrimidines, allowing it to be used in the design and synthesis of potent inhibitors for enzymes like dihydroorotate dehydrogenase (DHODH), a target in autoimmune and proliferative diseases.

    Agrochemical Research: Applied in the synthesis of novel compounds with potential herbicidal or fungicidal activities.

    Why Source From Us?

    We specialize in supplying high-value chemical building blocks to global industry leaders. Our 5-Bromo-6-azauracil is manufactured under strict quality control protocols, ensuring >98% purity (as verified by HPLC/NMR). We provide comprehensive analytical data, secure packaging, and flexible scaling from grams to commercial quantities. Partner with us to fuel your innovation with reliability and expertise.

    Key SEO & Marketing Elements Integrated:

    Keywords: Molecular building block, nucleobase analog, pharmaceutical intermediate, brominated uracil, cross-coupling, Suzuki, nucleoside synthesis, enzyme inhibitor, DHODH, high-purity, CAS number (implied).

    Target Audience Language: Uses terms like "medicinal chemistry," "drug discovery," "synthetic intermediate," "library synthesis," and "target molecules" that resonate with R&D scientists and managers.

    Value Proposition: Emphasizes quality (QC, HPLC/NMR), reliability (batch-to-batch consistency), and scalability (grams to kilos) crucial for business-to-business procurement.

    Call to Action: The "Why Source From Us" section directly addresses the needs of a corporate buyer, building trust and encouraging contact or purchase.

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