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Intermediates 5-Fluoro-4-Methyl-2-nitrophenol for critical molecular building block
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Intermediates 5-Fluoro-4-Methyl-2-nitrophenol for critical molecular building block

CAS:83341-28-0 

Product purity:98% Appearance:Yellow powder

5-Fluoro-4-Methyl-2-nitrophenol | High-Purity Building Block

5-Fluoro-4-Methyl-2-nitrophenol is a high-purity, multifunctional chemical building block specifically designed for pharmaceutical research and development. This compound features a unique molecular structure incorporating fluorine, a nitro group, and a phenolic hydroxyl group, making it an exceptionally versatile intermediate for constructing complex molecules.

It is primarily used in the synthesis of advanced pharmaceutical intermediates and active pharmaceutical ingredients (APIs). The presence of fluorine often enhances metabolic stability, bioavailability, and binding affinity. The nitro and hydroxyl groups provide reactive sites for further functionalization, facilitating efficient parallel synthesis and lead optimization in drug discovery programs, particularly in agrochemical and material science applications.

Our product guarantees exceptional purity and consistent quality, supporting reliable and reproducible research outcomes.

    5-Fluoro-4-Methyl-2-nitrophenol: A Versatile Molecular Building Block for Advanced R&D

    Product Overview
    5-Fluoro-4-Methyl-2-nitrophenol is a sophisticated and highly pure chemical building block engineered for critical applications in medicinal chemistry and drug discovery. Its structure, which integrates a fluorine atom, a methyl group, a nitro group, and a phenolic hydroxyl group on a benzene ring, offers multiple vectors for chemical modification, making it an invaluable asset for synthetic chemists.

    Key Applications & Uses
    This compound serves as a crucial intermediate in the synthesis of complex target molecules. Its primary application lies in developing novel Active Pharmaceutical Ingredients (APIs) and advanced intermediates for potential therapeutics. The strategic incorporation of fluorine is a well-established method to fine-tune the physicochemical properties of drug candidates, potentially improving their metabolic stability, membrane permeability, and overall pharmacokinetic profile. The reactive nitro group is a key handle for further transformations, such as reduction to an aniline or participation in nucleophilic aromatic substitution, while the phenolic OH group allows for etherification or esterification. This versatility accelerates the exploration of structure-activity relationships (SAR) during lead optimization phases in pharmaceutical and agrochemical research.

    Quality & Supply Assurance
    We specialize in supplying this and other high-quality molecular building blocks to the global research community. Our rigorous quality control protocols, including detailed HPLC and NMR analysis, ensure batch-to-batch consistency and high purity (>97% typically), providing the reliability essential for your most demanding R&D projects. Contact us for custom synthesis inquiries and comprehensive product documentation.

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