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Intermediates Carboxymethoxylamine hemihydrochloride for critical molecular building block
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Intermediates Carboxymethoxylamine hemihydrochloride for critical molecular building block

CAS:2921-14-4 

Product purity:98% Appearance:White crystal

Title: High-Purity Carboxymethoxylamine Hemihydrochloride | Building Block for Medicinal Chemistry

As a key molecular building block, Carboxymethoxylamine Hemihydrochloride (O-Carboxymethylhydroxylamine hemihydrochloride) is an essential reagent for sophisticated organic synthesis. This compound is primarily recognized for its crucial role in oxime and hydrazone ligation chemistries, serving as a versatile linker for bioconjugation. It enables the stable conjugation of biomolecules, such as proteins, peptides, and antibodies, with various probes, drugs, or other functional entities.

Our product is manufactured under strict ISO quality controls, guaranteeing exceptional purity and batch-to-batch consistency ideal for R&D and scale-up. It is an indispensable tool for pharmaceutical researchers developing advanced biotherapeutics, diagnostic assays, and ADC (Antibody-Drug Conjugate) platforms. Trust our expertise to supply the critical compounds that accelerate your innovation.

    Carboxymethoxylamine Hemihydrochloride | Bioconjugation Reagent & Molecular Building Block

    Product Overview

    Carboxymethoxylamine Hemihydrochloride is a high-value, multifunctional molecular building block specifically engineered for advanced medicinal chemistry and bioconjugation applications. This white to off-white crystalline powder serves as a critical precursor for introducing oxime functionality into complex molecules, facilitating the creation of stable, bioorthogonal linkages under mild physiological conditions.

    Key Applications & Uses

    Bioconjugation & ADC Development: Expertly used to conjugate carbonyl-containing molecules (like aldehydes or ketones) to amine-containing molecules. It is a cornerstone reagent in the synthesis of Antibody-Drug Conjugates (ADCs), enabling the precise attachment of potent cytotoxins to monoclonal antibodies.

    Chemical Biology & Proteomics: Facilitates site-specific protein labeling, immobilization on solid supports, and the development of sensitive diagnostic immunoassays.

    Organic Synthesis: Acts as a versatile synthon for constructing heterocycles and other complex molecular architectures in pharmaceutical intermediates.

    Quality & Supply Assurance

    Supplied as a high-purity compound, our Carboxymethoxylamine Hemihydrochloride undergoes rigorous QC analysis (including NMR and HPLC) to ensure it meets the stringent requirements for pharmaceutical R&D and pre-clinical development. We provide comprehensive technical data sheets and are equipped to support your projects from initial discovery to commercial-scale production.

    Why Partner With Us?

    As a leader in the pharmaceutical building blocks sector, we combine deep R&D expertise with a global supply chain capability. We don't just supply chemicals; we provide solutions that empower your research and accelerate the journey from molecule to medicine. Contact our sales and scientific support team for custom synthesis inquiries and bulk pricing.

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